Listed on the National Register of Historic Places on 8/14/1986.

Developed in the late 19th century through the combined efforts of Spokane speculators and Jesuit missionaries, the Mission Avenue Historic District is the most intact remnant of the city's first residential suburbs and includes a significant collection of late 19th and early 20th century houses located on one of the city's oldest landscaped boulevards.  Seven blocks in length, the district is unified by the canopy of trees that divides the broad boulevard.  Facing the street on either side are a variety of Queen Anne, Four Square, Craftsman and Bungalow style houses that reflect the substantial architecture of the period and the original suburban character of the area.  While other parts of the boulevard have suffered from new construction, the district still reflects a period when the area was an impressive drive that formed the centerpiece of one of the city's finest residential neighborhoods.

Contributing Properties
220 E Mission Ave
227 E Mission Ave
228 E Mission Ave
302 E Mission Ave
307 E Mission Ave
308 E Mission Ave
312 E Mission Ave
315 E Mission Ave
318 E Mission Ave
328 E Mission Ave
329 E Mission Ave
402 E Mission Ave
407 E Mission Ave
413 E Mission Ave
414 E Mission Ave
417 E Mission Ave
418 E Mission Ave
424 E Mission Ave
428 E Mission Ave
429 E Mission Ave
504 E Mission Ave
509 E Mission Ave
511 E Mission Ave
517 E Mission Ave
518 E Mission Ave
524 E Mission Ave
525 E Mission Ave
528 E Mission Ave
604 E Mission Ave
610 E Mission Ave
611 E Mission Ave
618 E Mission Ave
624 E Mission Ave
630 E Mission Ave (Zeph Lane House)
702 E Mission Ave
714 E Mission Ave
724 E Mission Ave
728 E Mission Ave
802 E Mission Ave
803 E Mission Ave
807 E Mission Ave
808 E Mission Ave
811 E Mission Ave
814 E Mission Ave
817 E Mission Ave
818 E Mission Ave
824 E Mission Ave